Talk Colorado Wine & Colorado's Wine Country: Could Grape Seeds Fight Alzheimer's?

Friday, October 10, 2008

Could Grape Seeds Fight Alzheimer's?

Here's another article on the restorative qualities of wine. Under the headline, "Grape Seeds May Combat Alzheimer's: Extracts found in seeds could be key in treating neurodegenerative diseases; clinical trials to begin," Wine Spectator is reporting the following:

"Compounds commonly found in red wine and grape seeds may help treat and prevent Alzheimer's disease, according to new research from the Mount Sinai School of Medicine.

"The research, published in the Journal of Neuroscience, found that polyphenols derived from grape seeds during red winemaking (a family of compounds such as tannins, lignins and flavonoids) may be useful in fighting and preventing the degenerative disease, which attacks the brain. A four-month study, headed by Dr. Guilio Pasinetti, professor of neuroscience at the Mount Sinai School of Medicine, discovered that the polyphenols helped reduce the deterioration of brain functioning in the mice.

"Pasinetti and his team gave nonlethal doses of grape seed extract to genetically modified mice that had attributes of Alzheimer’s disease. In studying the cognitive functionality of the animals following treatment, the researchers found that the polyphenolic extract from grape seeds helped prevent the formation of a beta-amyloid, which can cause a blockage in the brain, or plaques that have been implicated in memory loss and Alzheimer's. Tested animals modified with Alzheimer's were found to retain their normal brain function after doses of the grape derivative."

You can read about the rest of the medical findings here.

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